Charlie Villanueva is a Dominican-American former professional basketball player. He was drafted at the age of 20 with the seventh overall pick in the 2005 NBA draft by the Toronto Raptors.

Villanueva played for the NBA's Toronto Raptors, Milwaukee Bucks, Detroit Pistons and Dallas Mavericks. He also holds Dominican citizenship and has represented the Dominican Republic national team in international competitions. Villanueva has an autoimmune skin disease known as alopecia universalis, a variation of alopecia areata. This prevents the growth of hair on the scalp and/or elsewhere on the body, but otherwise is not physically painful, dangerous, or life-threatening. Villanueva is a spokesman for the NAAF (National Alopecia Areata Foundation), and received the February 2006 Community Assist Award from the NBA for his work with the organization. A first-generation Dominican-American, Villanueva is fluent in Spanish, as it is the language he speaks with his family.

Villanueva has three brothers and as of September 2015, Charlie is working with two of his three brothers on a documentary, called "What is Alopecia", based on the autoimmune disease Alopecia Areata, in order to continue his advocacy efforts to educate, create awareness and support the Alopecia community.